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Environmental factors like temperature, light, and moisture can compromise the product, leading to degradation of the benzyl alcohol preservative or even promoting microbial growth if conditions are unfavorable

So have too much B12, never thought I'd say that

doi: 10.1152/ajpheart.00535.2010 198 MaSWangJLinJJinSHeFMeiJet al

In the following years, studies revealed a significant decrease of complex I activity in the SN of patients with idiopathic PD [83, 84], as well as reduced activity of complexes I and IV in peripheral blood [85]

But some nutrients have a more complicated story, and vitamin B12 is a fascinating example